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Oral alcohol self-administration and maintenance of operant behavior in rats

In recent years, researchers have developed experimental models of oral self-administration of alcohol to study the effects of different variables on alcohol consumption in rats (Linseman, 1987; Tabakoff & Hoffman, 2000). According to Kamenetzky and Mustaca (2005), home cage and operant conditioning models are the two main forms of self-administration of alcohol in animals. The main difference between both models is the behavioral requirement established to have access to alcohol. In two cases the animal controls the temporal pattern of intake and dose.